PLUMMER VINSON SYNDROME

This is one of the commonest, preventable, treatable causes of dysphagia in women. Iron deficiency anemia is due to improper diet habits and inattention to abnormal blood loss in women.

      Irrespective of educational, economic status, women slip into anemia inadvertently. Anemia is almost always accompanied by vitamin deficiency.

      This results in drying and transformation of the lining epithelium of oral cavity and hypopharynx resulting in difficulty in passage of food.

      In severe cases cricopharyngeal sphincter hardens and forms a web. There were even occasions where in attempt to swallow a tablet has caused obstruction which were cleared by endoscopy under GA.

      Another co-marbidity to this condition is presence of hyper acidity syndrome leading to oral iron intolerance and hampering the intrinsic factor availability, making the oral iron therapy difficult and ineffective.

      Hence parenteral iron along with other nutritional factors like B12, folic acid etc., is the treatment of choice.

      The investigations to be done to clinch the diagnosis are Complete Haemogram including peripheral smear to study the type of anemia. Barium swallow to demonstrate a web and to rule out any other pathology.

      In rare occasion oesophagoscopic dilatation under general anesthesia has to done to get adequate passage for swallowing.

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